Capabilities / Technical strength

Allchem Laboratories has a wide spectrum of Reaction Capabilities that can be intelligently combined to open up new opportunities for complex molecules

Production process involves

  • Reaction
  • Distillation (at atmospheric and under vacuum up to 0.05 mm Hg)
  • Filtration (using sparkler filter, centrifuge, Nutch filter)
  • Extraction
  • Hydrogenation reaction up to 15 kg/cm2
  • Crystallization & purification
  • Drying (using tray dryer, fluid bed dryer )
  • Milling, Blending
  • Packing under nitrogen / Argon

Reaction Capabilities

  • Acetylation, Acylation (Fridel craft reaction)
  • Acid chloride reaction, Amide, Ester, amide formation
  • Alkylations of -C, -N, -S, -O etc…..
  • Bromination (Side chain as well as aromatic ring)
  • Cyanation (Side chain as well as ring)
  • Dieckmann Cyclization
  • Gabriel synthesis
  • Grignard reaction
  • High Vacuum distillation (up to 0.005 mm of Hg)
  • Hydrogenation reaction (with Ni, 5% Pd and 5% Rh on C)
  • Hydrolysis of esters, decarboxylation, amides and Nitriles
  • Koevenagel condensation
  • Liquid ammonia reaction
  • Low temperature reaction (-70 deg C)
  • Phase transfer reaction
  • Sandmayer reaction, diazotization reaction etc…
  • Stork Enamine reaction
  • Substitution
  • Vilsmeier-Haack reaction

Handling of Hazardous chemicals like….

  • Thionyl chloride & Phosphorous oxychloride
  • Aluminum chloride anhydrous during fridel craft acylation
  • Grignard reagents
  • Sodium methoxide and sodium ethoxide generation
  • All flammable solvents like toluene, ether, Xylene, methanol, MDC, acetone, IPA, hexane, DMF etc…….
  • Dry HCl gas generation as well as use at plant level
  • All types of acids and strong bases
  • Acid chlorides and anhydrides
  • Raney Nickel, Precious metal catalyst (Pd, Pt, Rh, Ru etc…)  in autoclave
  • Sodium borohydride & Lithium aluminum hydride for reduction at low as well as high temp.
  • Low temperature reactions using dry Ice (up to -70 deg C)